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. 2021 Jul 1;22(13):7105. doi: 10.3390/ijms22137105

Figure 1.

Figure 1

Figure 1

CCI induced mechanical allodynia and increased TSLP levels in L4/5 DRGs. (A) Behavioral data demonstrating the reduction of PWT though calibrated forceps test after CCI. The control group received no sciatic nerve ligation. N = 12 for each group. *** p < 0.001 vs. control group analyzed by ANOVA test. (B) Immunofluorescence staining showing increased astrocyte reaction in the L4/5 dorsal spinal cord of rats after CCI. Scale bar, 100 μm. (C) Relative fluorescence intensity of GFAP. (D) Western blot analysis showing increased TSLP protein expression in L4/5 DRGs of rats after CCI. Each band density was quantitated, normalized with its own β-actin. Values are presented as mean ± SEM. N = 6 for each group. * p < 0.05, ** p < 0.01 and *** p < 0.001 vs. control group analyzed by ANOVA test.