Table 1.
Baseline characteristics in patients treated before and after the implementation of advanced neuroimaging.
| Baseline Characteristics | AN− (n = 29) |
AN+ (n = 47) |
p-Value |
|---|---|---|---|
| Age, years (mean, SD) | 63 ± 16 | 73 ± 13 | 0.003 |
| Weight, kg (mean, SD) | 82 ± 18 | 80 ± 21 | 0.631 |
| Smoking (%) | 27.6% | 25.5% | 0.850 |
| Hypertension (%) | 72.4% | 57.4% | 0.189 |
| Diabetes (%) | 31.0% | 17.0% | 0.154 |
| Hypercholesterolemia (%) | 27.6% | 42.6% | 0.189 |
| Prior stroke (%) | 3.4% | 4.3% | 0.861 |
| Prior TIA (%) | 0.0% | 6.4% | 0.165 |
| Congestive heart failure (%) | 3.0% | 0.0% | 0.200 |
| Valvular disease (%) | 6.9% | 0.0% | 0.068 |
| Coronary artery disease (%) | 10.3% | 4.3% | 0.298 |
| Peripheral Arterial Disease (%) | 3.4% | 6.4% | 0.578 |
| Extended window 4.5–9 h (%) | 0.0% | 14.9% | 0.029 |
| Wake up stroke (%) | 3.4% | 8.5% | 0.387 |
| Extended window or wake up | 3.4% | 23.4% | 0.020 |
| NIHSS-score on admission, points (median, IQR) | 4 (2–7) | 5 (4–9) | 0.047 |
| Systolic BP on admission, mmHg (mean ± SD) | 152 ± 34 | 153 ± 21 | 0.837 |
| Diastolic BP on admission, mmHg (mean ± SD) | 80 ± 15 | 82 ± 14 | 0.549 |
| Platelet count on admission, ×109/L (mean ± SD) | 267 ± 152 | 228 ± 83 | 0.477 |
| LDL on admission, mg/dL (mean ± SD) | 137.5 ± 49 | 129.5 ± 34 | 0.554 |
| Glucose on admission, mg/dL (mean ± SD) | 129 ± 39 | 129 ± 39 | 0.174 |
| Onset-to-imaging time, min (median, IQR) | 105 (87.5–161) | 160 (120–202.5) | 0.011 |
| Door-to-needle time, min (median, IQR) | 43.5 (36–60) | 45 (30–61) | 0.956 |
| Onset-to-treatment time (median, IQR) | 121 (110–153) | 197.5 (151–240) | <0.001 |
| ASPECTS (median, IQR) | 10 (9–10) | 10 (9–10) | 0.278 |
| Duration of Hospitalization (median, IQR) | 10 (8–18) | 9.5 (5–16.5) | 0.725 |
| Location of stroke in the left hemisphere (%) | 43.2% | 56.8% | 0.564 |
| Location of stroke in posterior circulation (%) | 34.5% | 19.1% | 0.199 |
| Hyperdense vessel sign in CT (%) | 3.6% | 4.3% | 0.870 |
| MR imaging (%) | 6.9% | 10.6% | 0.584 |
| Thrombus length, mm (median, IQR) | 8.5 (5.75–14) | 12 (9–20) | 0.053 |
| Large Vessel occlusion (%) | 17.2% | 19.1% | 0.835 |
| Medium Vessel Occlusion (%) | 44.8% | 40.4% | 0.706 |
Blood pressure, BP; National Institute of Health Stroke Scale, NIHSS; interquartile range, IQR; Alberta Stroke Program Early CT score, ASPECTS; standard deviation, SD.