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. 2021 Jun 28;22(13):6950. doi: 10.3390/ijms22136950

Table 1.

Screening of the effect of the present selected compounds on the inhibition of the growth of bacterial and fungal strains (own research results). Approximate values of the minimum inhibitory concentration (MIC).

Compound Growth Inhibition Concentration (mg/mL)
Escherichia coli Pseudomonas aeruginosa Staphylococcus epidermidis Staphylococcus aureus Candida albicans Aspergillus brasiliensis
1 Zn[(acac)2 H2O] 1
after 24 and 48 h
average
10
after 24 and 48 h
average
10
after 24 and 48 h
average
1
after 24 and 48 h
average
1
after 24 and 48 h
average
10
after 24 and 48 h
average
2 Spermidine 10
after 24 and 48 h
average
10
after 24 and 48 h
average
1
after 24 and 48 h
average
1
after 24 and 48 h
total
1
after 24 and 48 h
total
10
after 24 and 48 h
average
3 Putrescine 10
after 24 and 48 h
total
10
after 24 and 48 h
total
10
after 24 and 48 h
Total
10
after 24 and 48 h
total
10
after 24 and 48 h
total
10
after 24 and 48 h
average
4. Phenylalanine 10 >
not observed
10
after 24 and 48 h
minimal
10
after 24 and 48 h
minimal
10
after 24 and 48 h
minimal
10
after 24 and 48 h
minimal
10
after 24 and 48 h
minimal
5 Schiff base HTrp 10
total after 48 h
10
after 24 h
average
1
after 24 and 48 h
average
10
total after 48 h
average
1
after 24 and 48 h
average
1
after 24 and 48 h
average
6 Schiff base HPhe 10
after 24 and 48 h
average
10
after 24 and 48 h
average
1
after 24 and 48 h
average
10
after 24 and 48 h
average
10
after 24 and 48 h
average
1
after 24 and 48 h
average
7 Zn[(acac)(LTrp)H2 O] 0.1
after 48 h
average
1
after 24 and 48 h
average
0.1
minimal
0.1
after 24 and 48 h
average
1
after 24 and 48 h
average
0.1
after 24 and 48 h
average
10 >
minimal
8 Zn[(acac)(LPhe)H2O] 0.1
after 24 and 48 h
average
1
after 24 h
total
0.1
after 48 h
total
0.1
after 24 h and 48 h
average
0.1
after 24 and 48 h
average
1
after 24 and 48 h
average
1
after 48
total

Note: after 24 and 48 h—after 24 h and 48 h of incubation; minimal—decrease in the number of cells by no more than 50%; average—decrease in the number of cells from 50% to 90%; total—decrease in the number of cells by more than 99.9%, compared to the number of cells in the control sample.