Table 1.
Compound | Growth Inhibition Concentration (mg/mL) | ||||||
---|---|---|---|---|---|---|---|
Escherichia coli | Pseudomonas aeruginosa | Staphylococcus epidermidis | Staphylococcus aureus | Candida albicans | Aspergillus brasiliensis | ||
1 | Zn[(acac)2 H2O] | 1 after 24 and 48 h average |
10 after 24 and 48 h average |
10 after 24 and 48 h average |
1 after 24 and 48 h average |
1 after 24 and 48 h average |
10 after 24 and 48 h average |
2 | Spermidine | 10 after 24 and 48 h average |
10 after 24 and 48 h average |
1 after 24 and 48 h average |
1 after 24 and 48 h total |
1 after 24 and 48 h total |
10 after 24 and 48 h average |
3 | Putrescine | 10 after 24 and 48 h total |
10 after 24 and 48 h total |
10 after 24 and 48 h Total |
10 after 24 and 48 h total |
10 after 24 and 48 h total |
10 after 24 and 48 h average |
4. | Phenylalanine | 10 > not observed |
10 after 24 and 48 h minimal |
10 after 24 and 48 h minimal |
10 after 24 and 48 h minimal |
10 after 24 and 48 h minimal |
10 after 24 and 48 h minimal |
5 | Schiff base HTrp | 10 total after 48 h |
10 after 24 h average |
1 after 24 and 48 h average |
10 total after 48 h average |
1 after 24 and 48 h average |
1 after 24 and 48 h average |
6 | Schiff base HPhe | 10 after 24 and 48 h average |
10 after 24 and 48 h average |
1 after 24 and 48 h average |
10 after 24 and 48 h average |
10 after 24 and 48 h average |
1 after 24 and 48 h average |
7 | Zn[(acac)(LTrp)H2 O] | 0.1 after 48 h average |
1 after 24 and 48 h average 0.1 minimal |
0.1 after 24 and 48 h average |
1 after 24 and 48 h average |
0.1 after 24 and 48 h average |
10 > minimal |
8 | Zn[(acac)(LPhe)H2O] | 0.1 after 24 and 48 h average |
1 after 24 h total 0.1 after 48 h total |
0.1 after 24 h and 48 h average |
0.1 after 24 and 48 h average |
1 after 24 and 48 h average |
1 after 48 total |
Note: after 24 and 48 h—after 24 h and 48 h of incubation; minimal—decrease in the number of cells by no more than 50%; average—decrease in the number of cells from 50% to 90%; total—decrease in the number of cells by more than 99.9%, compared to the number of cells in the control sample.