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. 2021 Jun 22;22(13):6673. doi: 10.3390/ijms22136673

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Clustering of differentially expressed genes (DEGs). (A) The volcano graph was performed to show DEGs in the yolk-cell period. The red part indicates up-regulated genes and the green part indicates down-regulated genes. (B) The overall distribution of DEGs between the WT group and wnt16^−/− group in the yolk-cell period. Red and green represent up-regulated and down-regulated changes, respectively, in the clustering analysis. The color intensity is directly proportional to the change. (C) Venn diagram of the co-expressed differential genes of three groups.