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. 2021 Jun 30;13(13):3273. doi: 10.3390/cancers13133273

Figure 2.

Figure 2

Flowchart representing the management algorithm using the three-tier classification in WLI and Ni 2019 classification in NBI in predicting high- and low-risk leukoplakia. Low-risk WLI: type 1 and 2 and high-risk WLI: type 3 acc. to Chen 2019 classification; low-risk NBI: type 1, 2, 3, 4 and high-risk WLI: type 5 and 6 acc. to Ni 2019 classification. Abbreviations used: VFL—vocal fold leukoplakia; WLI—white light imaging; NBI—Narrow Band Imaging; CT—conservative treatment; TOLMS—Transoral Laser Microsurgery; * under general anesthesia; ** referral to external NBI center.