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. 2021 Jun 30;22(13):7088. doi: 10.3390/ijms22137088

Figure 3.

Figure 3

Overall immobility and 22-kHz total calling time. Effects of SERT deficiency on overall immobility and 22-kHz USV total calling time during acquisition (A,B), extinction (C,D), and recovery (E,F). Time spent immobile is shown for SERT+/+ (black bar), SERT+/− (striped bar), and SERT−/− (white bar) rats with sexes pooled (A,C,E) and separated by sex (A,C,E), with females on the left and males on the right side of the panel. Time spent calling 22-kHz USV is shown for rats with sexes pooled (B,D,F) and separated by sex (B,D,F), with females on the left and males on the right side of the panel. N = 44 female rats (15 +/+, 15 +/−, 14 −/−), N = 43 male rats (14 +/+, 15 +/−, 14 −/−). Data are presented as mean ± SEM. G* p < 0.05 effect of genotype, with lines indicating significant post-hoc comparison between genotypes. S* p < 0.05 effect of sex. * p < 0.05 for subgroup comparison.