Table 2.

Parameters of liver steatosis, inflammation, fibrosis, and apoptosis in mice fed a control diet (CD30) and Western-style diet (WD30) for 30 weeks.

	Parameter	CD30	WD30
Steatosis	TGs, µmol/g tissue	29.79 ± 8.63	169.00 ± 1.98 **
	Cholesterol, µmol/g tissue	6.61 ± 0.52	75.72 ± 12.69 **
Inflammation	TNF-α, ng/mg protein	8.83 ± 1.14	21.82 ± 5.19 **
	IL-6, ng/mg protein	17.31 ± 4.30	53.14 ± 12.82 **
Fibrosis	TGF-β rel. gene expression	0.645 ± 0.190	1.180 ± 0.124 **
	TGF-β rel. protein expression	0.044 ± 0.072	0.030 ± 0.044
	TIMP-1 rel. gene expression	0.532 ± 0.252	21.29 ± 2.804 **
	TIMP-1 rel. protein expression	0.209± 0.100	0.197± 0.053
	Col1A2 rel. gene expression	0.628 ± 0.250	5.220 ± 0.894 **
	Col1A2 rel. protein expression	17.15 ± 0.2.07	23.51 ± 2.78 **
	α-SMA rel. gene expression	1.667 ± 1.000	5.386 ± 1.872 **
	α-SMA rel. protein expression	0.036 ± 0.006	0.125 ± 0.074 *
Apoptosis	Bcl-2 rel. gene expression	0.532 ± 0,252	21.290 ± 2.80 **
	Bcl-2 rel. protein expression	0.097 ± 0.030	0.138 ± 0.024 *
	p53 rel. gene expression	0.725 ± 0.165	0.820 ± 0.053 *
	p53 rel. protein expression	0.070 ± 0.043	0.282 ± 0.103 **
	p21 rel. gene expression	0.606 ± 0.228	6.210 ± 1.468 **
	p21 rel. protein expression	0.391 ± 0.138	0.681 ± 0.188 *
	Bax rel. gene expression	0.913 ± 0.177	1.308 ± 0.154 **
	Bax rel. protein expression	0.184 ± 0.064	0.169 ± 0.028
	Panx1 rel. gene expression	0.693 ± 0.171	1.718 ± 0.207 **
	Panx1 rel protein expression	0.040 ± 0.019	0.089 ± 0.021 **

The results are expressed as the means ± SD; * p < 0.05, ** p < 0.01 (n = 6 each group).