Table 2.
The list of cell lines and tumors with impact of EPOR/STAT5 signaling on the cell processes.
| Cell Line/Tumor Type | Effect of EPOR/STAT5 | References |
|---|---|---|
| Myeloproliferative neoplasms, secondary acute myeloid leukemia | Cell survival, proliferation and migration | [51] |
| Prostate cancer cell lines, primary prostate tissue | Proliferation | [38] |
| Erythroleukemic cell lines | Cell survival | [39] |
| Neuronal differentiated neuroblastoma SH-SY5Y, Pheochromocytoma PC-12 | Cell survival | [40] |
| Breast cancer cells | Cell survival | [41] |
| Non-small-cell lung carcinoma (NSCLC) cell line H838 | Cell survival | [45] |
| NSCLC cell lines A427, A549, and NCI-H358 cell lines | No effect | [46] |
| Head and neck squamous cell carcinoma cells | Tumor invasion | [48] |
| Multiple myeloma endothelial cells (MMEC) | Angiogenesis | [52] |
| Benign non-invasive rat mammary cell lines stably transfected with human EPOR | Malignant cell behavior | [42] |