Figure 1.

Cumulative risk of developing cancer in patients with LS according to the type of mismatch repair gene mutation by the age of 80. Dark and light blue bars indicate the lower and upper cumulative risk, respectively, for each cancer type. The red numbers above each bar represent the estimated mean age at presentation for each cancer type. Asterisks (*) and double asterisks (**) indicate that limited or no data are available for the mean age at presentation and the cumulative cancer risk, respectively.