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HOTAIR ISH signals localization: (a) HOTAIR nuclear mRNA expression with 4–5 dots/cell in neoplastic cells (40× magnification); (b) HOTAIR nuclear and cytoplasmic mRNA cluster expression in neoplastic cells (40× magnification); (c) HOTAIR cytoplasmic mRNA expression, >4 dots/cell in neoplastic cells (40× magnification). White arrows showing nuclear expression while red arrows showing cytoplasmic expression.
