Table 2.
ANOVA test comparing the urinary concentration of the evaluated cytokines in patients with ATIN, ATN, and healthy controls. * Statistically significant differences. ATIN—acute tubulointerstitial nephritis; ATN—acute tubular necrosis.
| ATIN (n = 21) | ATN (n = 12) | Healthy Controls (n = 6) |
p-Value | |
|---|---|---|---|---|
| I-TAC/CXCL11 | 129.5 ± 64.68 | 23.07 ± 19.01 | 2.35 ± 1.07 | 0.046 * |
| MIG/CXCL9 | 1170 ± 739.5 | 1456 ± 896.2 | 43.37 ± 9.91 | 0.665 |
| IL1B | 9.08 ± 5.84 | 14.56 ± 9.73 | 2.03 ± 0.53 | 0.241 |
| CXCL10 | 909.9 ± 468.1 | 58.60 ± 16.74 | 35.31 ± 15.3 | 0.105 |
| IL6 | 323.1 ± 235.1 | 24.09 ± 8.11 | 3.2 ± 0.2 | 0.029 * |
| IL17 | 7.28 ± 5.15 | 4.67 ± 2.37 | 2.18 ± 0.65 | 0.83 |
| TNFα | 5.46 ± 1.12 | 4.17 ± 0.89 | 2.84 ± 0.27 | 0.032 * |
| IFNα | 23.04 ± 13.82 | 18.21 ± 6.99 | 27.48 ± 13.8 | 0.669 |
| MCP1 | 12848 ± 4413 | 2221 ± 603.2 | 418 ± 217.6 | 0.002 * |
| EGF | 3888 ± 851.3 | 3067 ± 1207 | 18748 ± 6454 | 0.003 * |