Extracellular enzyme activities as determined with API-ZYM system (alkaline phosphatase (A), esterase C4 (B), esterase lipase C8 (C), lipase C14 (D), leucine arylamidase (E), valine arylamidase (F), cysteine arylamidase (G), trypsin (H), α-chymotripsin (I), acid phosphatase (J), naphthol-AS-BI-phosphohydrolase (K), α-galactosidase (L), β-galactosidase (M), β-glucuronidase (N), α-glucosidase (O), β- glucosidase (P), N-acetyl-β-glucosaminidase (Q), α-mannosidase (R), α-mannosidase (S)). According to this scale, enzyme activities were scored as following: 0—no color, 1—low, 2—moderate and 3—high.