Figure 5.

PCu inhibits Cu²⁺-mediated Aβ deposition in N2a-sw cells. N2a-sw cells were treated with 50 μM of Cu(II) or co-incubated with 100 μM PCu for 12 h. (A) Extracellular Aβ secretion is measured using ELISA. (B) Representative photomicrographs of Aβ fluorescence in the N2a-sw cells. Scale bar: 20 μm. (C) Detection of the intracellular copper content using ICP-MS. The data represent the mean ± S.E. of 3 independent experiments. ** p < 0.01; *** p < 0.001 compared to the Cu²⁺-damaged group.