Figure 1.

Locally advanced rectal carcinoma genome for the 39 patients genotyped on the Affymetrix SNP array 6.0 platform. A summary plot showing the frequency of gains (in red below zero values on the x-axis) and losses (in blue above zero values on the x-axis) identified in samples obtained prior to therapy are shown for the whole genome. Those chromosomal regions most commonly showing recurrent losses and gains were localized in chromosomes 1p, 4q, 8p, 14q, 15q, 17q, 18q, and 22q, and in the 8q, 15q, and 20q chromosomal regions, respectively (q < 0.001) and are indicated *.