Table 2.
The summarized results of antimicrobial properties of the tested lipopeptides.
| Compound | MIC100 [µg/mL] | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
C.albicans
CCM 8186 |
C.krusei
CCM 8271 |
C.parapsilosis
CCM 8260 |
C.glabrata
CCM 8270 |
B. subtilis
PCM 2224 |
B. cereus
PCM 482 |
S. epidermidis
PCM 2118 |
S. aureus
PCM 2054 |
E. coli
PCM 2057 |
P. aeruginosa
PCM 499 |
|
| C5-CAR | Non-inhibitory | |||||||||
| AHX-CAR | ||||||||||
| C12-CAR | ||||||||||
| C16-CAR | ||||||||||
| C5-DK5 | 6.25 | 25 | 3.13 | 6.25 | 0.78 | 12.5 | 0.78 | 12.5 | 3.13 | 25 |
| AHX-DK5 | 12.5 | 50 | 12.5 | 12.5 | 0.78 | 50 | 0.78 | >50 | 12.5 | 25 |
| C12-DK5 | 3.13 | 3.13 | 3.13 | 3.13 | 0.78 | 12.5 | 0.78 | 6.25 | 12.5 | 12.5 |
| C16-DK5 | >50 | 6.25 | 12,5 | >50 | 3.13 | >50 | 25 | >50 | >50 | >50 |
| C5-CAR-PEG-DK5 | >50 | >50 | 50 | >50 | 6.25 | >50 | 6.25 | >50 | >50 | >50 |
| AHX-CAR-PEG-DK5 | >50 | >50 | 50 | >50 | 6.25 | >50 | 6.25 | >50 | >50 | >50 |
| C12-CAR-PEG-DK5 | 12.5 | 12.5 | 3.13 | 12.5 | 3.13 | >50 | 0.78 | 6.25 | 3.13 | 12.5 |
| C16-CAR-PEG-DK5 | 25 | 12.5 | 6.25 | >50 | 12.5 | >50 | 25 | >50 | >50 | >50 |
| DK5 | 31.3 | 7.8 | 31.3 | 62.5 | 15.6 | >50 | 7.8 | >50 | >50 | 50 |
| CAR-PEG-DK5 | 15.6 | 3.9 | 31.3 | 62.5 | 3.9 | >50 | 3.9 | >50 | >50 | 50 |