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. Author manuscript; available in PMC: 2021 Jul 9.
Published in final edited form as: J Psychopharmacol. 2019 Apr 30;33(7):831–841. doi: 10.1177/0269881119844185

Figure 2. Metabolism of methylone and corresponding monoamine uptake inhibition curves.

Figure 2.

Major (bold) and minor enzymes involved in methylone metabolism as described in (Pedersen et al., 2013). Monoamine uptake curves were fitted by non-linear regression and the data are presented as the mean±S.E.M. No DAT IC50 value was calculated for HHMC, due to the lack of sigmoidal shape of the uptake curve. The DAT uptake curve intercept between 0 and 100% for HHMC is shown in the figure for comparison and the full curve is shown in Supplemental Figure S1.