Table 2.
Study of proteomics. MetS, metabolic syndrome.
| Author, Year | Species | Cohort | Findings | Ref |
|---|---|---|---|---|
| Hsieh, 2016 | Animal | Male Sprague Dawley rats | High-fructose diet escalates oxidative stress, disturbing glucose and fatty acid metabolism. | [57] |
| Benade, 2020 | Male Wistar rats | Altered mitochondrial physiology predisposes cardiometabolic complications. | [58] | |
| Markova, 2019 | Male hereditary hypertriglyceridaemic rats | Dicarbonyl stress aggravated by methylglyoxal, causing renal dysfunction in MetS. | [60] | |
| Conceição, 2020 | ZSF1 rats | Obesity changes the proteomic expression, leading to myocardial consequences. | [61] | |
| Pla-Pagà, 2020 | Sprague Dawley rats | Hesperidin supplementation alters proteomic landscape and the risk of corresponding complications. | [62] | |
| Gueugneau, 2021 | Human | 30 healthy subjects, 9 patients with MetS | MetS promoted proteolysis and antagonizing oxidative phosphorylation. | [59] |
| Alfadda, 2017 | 18 Saudi obese patients | Metabolically unhealthy patients present differential levels of 18 proteins. | [63] | |
| Sharma, 2019 | 80 pre-menopausal females | History of miscarriage is correlated with MetS via transthyretin | [64] |