Figure 2.

Visually evoked potentials were recorded in RCS rats with transduced mVChR1 gene. The wavelength sensitivities (A) and stimulus intensity responses (B) of the VEPs in mVChR1 transduced rats (mean ± S.E., n = 4). The relationships between amplitudes and stimulus intensities correlated well. Values of Pearson’s r are shown in (B). Recorded amplitudes of the VEPs with a stimulus of 525 nm LED (C) and individual percentages compared to the pre-recorded values (D) after a series of continuous light exposures. mVChR1, modified volvox-derived channelrhodopsin-1; RCS, Royal College of Surgeons; VEP, visually evoked potential.