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. 2021 Jun 28;22(13):6959. doi: 10.3390/ijms22136959
TB trophoblasts
EV extracellular vesicles
HNDFs human normal dermal fibroblasts
TB-CM trophoblast-derived conditioned medium
TB-Exo trophoblast-derived exosomes
ECM extracellular matrix
MSCs mesenchymal stem cells
iPSCs induced pluripotent stem cells
MSC-CM MSC-derived conditioned medium
qRT-PCR quantitative real-time polymerase chain reaction
CCK8 cell counting kit 8
MMP matrix metalloproteinase
MSC-Exo MSC-derived exsomes
SA-β-Gal senescence-associated β-galactosidase
DEGs differentially expressed genes
KEGG Kyoto encyclopedia of genes and genomes
GO gene ontology
TGF-β transforming growth factor-beta
TLR3 toll-like receptor 3
GDF11 growth differentiation factor 11
IL-6 interleukin-6
STAT3 signal transducer and activator of transcription 3
NF-κB nuclear factor kappa B
VEGF vascular endothelial growth factor
HIPK4 homeodomain interaction protein kinase 4
ESCs embryonic stem cells
TSCs trophoblast stem cells
UVB ultraviolet B
FBS fetal bovine serum
PBS phosphate-buffered saline