FIG 6.

Functional characterization of the candidate microbiome between meningitis patients and healthy controls. (A) Cumulative relative abundance of metabolic functions enriched in the blood microbiota of children with BM. (B) Boxplot showing metabolic functions enriched in PB (P < 0.05, Wilcoxon rank sum test). The horizontal bars within boxes represent medians. The tops and bottoms of the boxes represent the 75th and 25th percentiles, respectively. The upper and lower whiskers extend to data no more than 1.5× the interquartile range from the upper edge and lower edge of the box, respectively. The numbers of replicated samples in this figure are as follows: n = 10 for NB and n = 31 for PB. (C) Pie charts showing proportions of different terms on metabolism functional categories in the NB and PB groups. The sector represents the proportion of each kind of pathway, and the percentages were calculated based on the mean relative abundance of the microbiomes.