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Molecular cartoon diagram of the 3D structure of SARS-CoV-2 spike protein monomer in the open form (cyan) in complex with receptor ACE-2 (green). The image was generated using PyMOL Molecular Graphics System version 1.7.0.3 software (Schrödinger, LLC) using cryo-EM data (Protein Data Bank accession number 7DF4 [36]). Amino acid substitutions found in B.1.1.7 (red), B.1.351 (orange), and P.1 (blue) variants are shown.
