Relative abundance patterns in environmental and culture metabolites. Each row is a metabolite—either identified or unknown. Left (A) is the standardized peak areas for metabolites in the culture data sets. Right (C) is the relative abundance between samples along the meridional transect. Tile panels are grouped separately using a k-medoids clustering and reordered within each mode for visual clarity. The middle panel (B) shows which metabolites are shared between the culture and environmental k-medoids-derived modes, with overenriched connections between modes shown in black (P < 0.05 by bootstrap test) and remaining non-statistically significant connections shown in gray. Organisms are colored by broad taxonomic classification as shown in inset (orange = cyanobacteria, gray = diatoms, yellow = dinoflagellates, purple = haptophytes, green = prasinophytes).