Table 2.
The results of the motor UHDRS assessment in HD patients.
| Variables/HD Stages | All HD | Very Early | Early | Intermediate | Advanced |
|---|---|---|---|---|---|
| ± SD | |||||
| Vertical pursuit | 1.13 ± 1.06 | 0.25 ± 0.45 | 0.56 ± 0.58 | 1.60 ± 1.24 | 2.20 ± 1.00 |
| Horizontal pursuit | 1.14 ± 1.09 | 0.16 ± 0.38 | 0.65 ± 0.57 | 1.60 ± 0.50 | 2.20 ± 1.00 |
| Vertical saccades initiation | 1.70 ± 1.29 | 0.25 ± 0.45 | 1.04 ± 0.47 | 2.36 ± 2.80 | 3.25 ± 0.55 |
| Horizontal saccades initiation | 1.67 ± 1.25 | 0.33 ± 0.65 | 1.04 ± 0.47 | 2.27 ± 1.14 | 3.20 ± 0.61 |
| Speed of horizontal saccades | 1.54 ± 1.18 | 0.25 ± 0.45 | 1.04 ± 0.47 | 2.09 ± 2.39 | 2.90 ± 0.78 |
| Speed of vertical saccades | 1.58 ± 1.2 | 0.25 ± 0.45 | 1.08 ± 0.51 | 2.12 ± 0.25 | 3.00 ± 0.72 |
| Dysarthria | 1.20 ± 1.02 | 0.16 ± 0.38 | 0.82 ± 0.49 | 1.45 ± 0.82 | 2.55 ± 0.82 |
| Tongue protrusion | 1.40 ± 1.36 | 0 ± 0 | 0.52 ± 0.84 | 2.00 ± 0.93 | 3.10 ± 0.55 |
| Bradykinesia (Tapping) of the right upper limb | 1.78 ± 1.42 | 0.25 ± 0.45 | 1.13 ± 0.54 | 2.18 ± 0.82 | 3.85 ± 0.36 |
| Bradykinesia (Tapping) of the left upper limb | 1.91 ± 1.48 | 0.25 ± 0.62 | 1.30 ± 0.82 | 2.45 ± 0.71 | 3.85 ± 0.36 |
| Pronation/supination of the left upper limb | 1.72 ± 1.29 | 0.33 ± 0.49 | 1.26 ± 0.61 | 2.09 ± 0.76 | 3.50 ± 0.68 |
| Pronation/supination of the right upper limb | 1.87 ± 1.33 | 0.33 ± 0.49 | 1.43 ± 1.33 | 2.39 ± 0.78 | 3.55 ± 0.68 |
| Luria’s test | 1.87 ± 1.64 | 0.50 ± 0.90 | 1.60 ± 1.64 | 2.12 ± 0.61 | 3.70 ± 0.57 |
| Left upper limb stiffness | 0.93 ± 1.06 | 0.08 ± 0.28 | 0.60 ± 1.06 | 1.06 ± 0.93 | 2.15 ± 1.08 |
| Right upper limb stiffness | 0.96 ± 1.05 | 0.08 ± 0.28 | 0.60 ± 1.05 | 1.15 ± 0.84 | 2.15 ± 1.08 |
| Bradykinesia | 1.44 ± 1.19 | 0.41 ± 0.66 | 1.21 ± 1.19 | 1.66 ± 0.90 | 2.80 ± 0.83 |
| Torso dystonia | 0.49 ± 0.78 | 0.08 ± 0.28 | 0.26 ± 0.78 | 0.54 ± 0.67 | 1.20 ± 0.95 |
| Right upper limb dystonia | 0.64 ± 1.03 | 0 ± 0 | 0.17 ± 1.03 | 0.63 ± 0.60 | 1.95 ± 1.27 |
| Left upper limb dystonia | 0.69 ± 1.09 | 0 ± 0 | 0.13 ± 1.09 | 0.75 ± 0.92 | 2.05 ± 1.27 |
| Right lower limb dystonia | 0.61 ± 0.99 | 0 ± 0 | 0.17 ± 0.99 | 0.69 ± 0.89 | 1.70 ± 1.21 |
| Left lower limb dystonia | 0.65 ± 1.02 | 0 ± 0 | 0.30 ± 1.02 | 0.72 ± 0.87 | 1.70 ± 1.17 |
| Facial chorea | 1.21 ± 1.09 | 0.08 ± 0.28 | 1.17 ± 1.09 | 1.51 ± 0.95 | 2.15 ± 1.13 |
| Oral-buccal-lingual chorea | 1.29 ± 1.24 | 0 ± 0 | 1.17 ± 1.24 | 1.57 ± 0.71 | 2.50 ± 1.27 |
| Torso chorea | 1.30 ± 1.13 | 0 ± 0 | 1.17 ± 1.13 | 1.81 ± 0.82 | 2.15 ± 1.26 |
| Left upper limb chorea | 1.44 ± 1.53 | 0.16 ± 0.38 | 1.56 ± 1.53 | 2.00 ± 0.93 | 2.00 ± 1.52 |
| Right upper limb chorea | 1.27 ± 1.17 | 0.08 ± 0.28 | 1.04 ± 1.17 | 1.87 ± 0.95 | 2.00 ± 1.52 |
| Left lower limb chorea | 1.38 ± 1.19 | 0 ± 0 | 1.26 ± 1.19 | 1.90 ± 1.06 | 2.30 ± 1.30 |
| Right lower limb chorea | 1.37 ± 1.17 | 0 ± 0 | 1.21 ± 1.17 | 1.87 ± 1.00 | 2.35 ± 1.30 |
| Gait | 1.27 ± 1.04 | 0.08 ± 0.28 | 0.82 ± 1.04 | 1.69 ± 0.96 | 2.55 ± 0.68 |
| Tandem gait | 1.58 ± 1.27 | 0.25 ± 0.45 | 1.04 ± 1.27 | 1.96 ± 0.76 | 3.30 ± 0.57 |
| Retropulsion | 1.11 ± 1.05 | 0 ± 0 | 0.86 ± 1.05 | 1.24 ± 0.86 | 2.50 ± 0.88 |
± SD—mean ± standard deviation.