Table 7.
Correlations between plasma levels of TGF-β1 and cognitive functions determined with Spearman’s test.
| Correlations/ HD Stages |
All HD | Preclinical | Very Early | Early | Intermediate | Advanced | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R | p | R | p | R | p | R | p | R | p | R | p | |
| TGF-β1 and VF Repetitions 0–60 s |
−0.25 | 0.01 | n.s. | n.s. | n.s. | n.s. | −0.43 | 0.04 | 0.39 | 0.02 | −0.57 | <0.01 |
| TGF-β1 and SWRT Correct answers |
n.s. | n.s. | n.s. | n.s. | n.s. | n.s. | −0.43 | 0.04 | n.s. | n.s. | n.s. | n.s. |
| TGF-β1 and SWRT Incorrect answers–corrected |
n.s. | n.s. | n.s. | n.s. | n.s. | n.s. | n.s. | n.s. | n.s. | n.s. | −0.46 | 0.04 |
| TGF-β1 and TMT part 1 Incorrect selections |
n.s. | n.s. | n.s. | n.s. | n.s. | n.s. | 0.42 | 0.04 | n.s. | n.s. | n.s. | n.s. |
R—Spearman’s correlation coefficient, n.s.—not statistically significant, VF—Verbal Fluency test, SWRT—Stroop Word Reading Test, TMT—Trail Making Test.