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The effect of vitamin D derivatives on the formation of small and large colonies by VDR KO cells and scramble controls. The number of colonies (% of ethanol control) with diameters of 0.1–0.5 and >0.5 mm for scramble (A) or WM164 VDR KO (B) cells was determined after 7 days of incubation with 1,20(OH)2D3 or 20(OH)D3 at the indicated concentrations. One-way ANOVA showed significant differences: p < 0.05 *, p < 0.01 **, p < 0.0001 ****, n = 6.
