Table 1.

Summary of HMG protein interactions with G4s and control oligonucleotides.

ODN	Kd, µM (HMGN3)	Kd, µM (HMGB2)	Kd, µM (HMGN1)
pG4s	1.5 ± 0.6	0.6 ± 0.3	0.2 ± 0.1 (N1–C3); 1.6 ± 0.3 (pos. contr.)
aG4s	>>20	>>20	≥20
mG4s	≥10 (M6); 0.15 ± 0.06 (M7)	4 ± 2 (M6); 1.6 ± 0.6 (M7)	≥10 (Tel 26); >20 (N1sh-2)
hairpin	≥20	≥20	≥10
dsDNA	>>20	>>20	>>20
ssDNA	>>20	>>20	>>20