Table 5.
Selected circRNAs identified in recent CCA studies.
| circRNA | Samples Analyzed | Expression in CCA | Primary Targets | Secondary Targets |
|---|---|---|---|---|
| circ-LAMP1 [98] | CCA tissues and cells | Upregulated | miR-556, miR-567 | YY1 |
| circ-CCAC1 [99] | CCA tissues and cells, bile EVs | Upregulated | miR-514a | YY1 |
| circ-DNM3OS [100] | CCA tissues and cells | Upregulated | miR-145 | MORC2 |
| circ-HIPK3 [101] | CCA tissues and cells | Upregulated | miR-148a-3p | ULK1 |
| circ-0000284 [102] | CCA tissues and cells | Upregulated | miR-637 | LY6E |
| circ-0005230 [103] | CCA tissues and cells | Upregulated | miR-1238, miR-1299 | N/A |
| circ-SMARCA5 [104] | CCA tissues | Downregulated | N/A | N/A |
| circ-0000673 [105] | CCA tissues | Upregulated | miR-548b-3p | Various genes predicted |