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. 2021 Jul 5;13(13):3376. doi: 10.3390/cancers13133376

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Representation of the “real-world” cohort of the study. (A) From an initial population of 161 patients, the histopathological review excluded samples without sufficient tumour cell content. Seventy tumour samples “gene driver free” and 55 MSI cases were eligible for RNA extraction and analysis, leading to a final cohort of 125 patients. (B) Final cohort composition: number of melanoma (MEL), colorectal cancer (CRC), and lung adenocarcinoma (LAC) patients according to gender, subdivided in “gene driver free”, and microsatellite instable (MSI) patients.