Figure 3.

Comparison of the distribution of fusion gene detection rates across “real-world” and in silico cohorts. (A) Graphical representation of the in silico microsatellite instable (MSI) cohort and the description of fusion prevalence in both the in silico and the “real-world” MSI cohorts. (B) Graphical representation of the cohort as a whole (top) and of the subgroups of cases according to the distinct histology and comparison between “real-world” and in silico data. The percentage of samples harbouring a fusion and significant p-values of the contingency tables are shown in a horizontal bar plot. Fusion positive cases are color-coded according to the legend (bottom-left). Dashed red lines separate the study cohort (“real-world”) from the in silico Memorial Sloane Kettering Cancer Centre (MSKCC) cohorts.