Table 1.
Baseline characteristics of patients with localized non-small cell lung cancer who were treated with stereotactic body radiation therapy.
| Patient Characteristics | Patients (n = 46) |
|---|---|
| Sex | |
| Female | 25 (54%) |
| Male | 21 (46%) |
| Age (years) | |
| Median (range) | 72 (52–87) |
| ≥70 years | 33 (72%) |
| Reason of SBRT referral | |
| Unfit for surgery 1 | 42 (91%) |
| Declined surgery | 4 (9%) |
| Histology | |
| Adenocarcinoma | 23 (50%) |
| Non-adenocarcinoma | 23 (50%) |
| Lung cancer stage | |
| 1A | 30 (65%) |
| 1B | 15 (33%) |
| Synchronous NSCLC | 1 (2%) |
| Prescribed radiation dose | |
| 45Gy/3F (BED 112Gy) | 4 (9%) |
| 66Gy/3F (BED 211Gy) | 42 (91%) |
| ECOG Performance Status | |
| 0–1 | 28 (61%) |
| ≥2 | 18 (39%) |
| Charlson Comorbidity Index | |
| 0–1 | 19 (41%) |
| 2–3 | 21 (46%) |
| >3 | 6 (13%) |
| Barthel-20 | |
| Normal (20–19) | 32 (70%) |
| Disability (≤18) | 14 (30%) |
| G-8 total (Abnormal ≤14) | |
| High (>14) | 13 (28%) |
| Intermediate (11–14) | 25 (54%) |
| Low (<11) | 8 (18%) |
| CST (n = 13) | |
| Normal (≥10) | 3 (23%) |
| Abnormal (<10) | 10 (77%) |
| HGST 2 | |
| Normal (♂ ≥ 21 kg/♀ ≥ 15 kg) | 35 (76%) |
| Abnormal (♂ < 21 kg/♀ < 15 kg) | 11 (24%) |
| G-8 + HGST | |
| Fit (normal G-8 and HGST) | 10 (22%) |
| Vulnerable (abnormal G-8 or abnormal HGST) | 26 (61%) |
| Frail (abnormal G-8 and HGST) | 8 (17%) |
| CGA 3 | |
| Yes | 24 (50%) |
| No | 22 (48%) |
ECOG Performance Status—Eastern Cooperative Oncology Group’s definition of performance status, G-8—Geriatric 8 screening tool, CST—Chair-stand test, HGST—Hand-grip strength test, ♂—male, ♀—female, G-8 + HGST—Combination of Geriatric 8 and hand-grip strength test, CGA—Comprehensive Geriatric Assessment. 1 Unfit for surgery encompasses patients considered medically inoperable or best served with SBRT. 2 Hand-grip strength measured using a Smedley Dynamometer. 3 Patients were randomized 1:1 to receive CGA or not upon inclusion in the previous randomized study.