Table 3.
Summary of mutations identified as causing agammaglobulinemia
| Mutation | Inheritance pattern |
|---|---|
| BTK (85%) | X-linked |
| Mu-heavy chain | AR |
| Lambda 5 | AR |
| Ig alpha | AR |
| Ig beta | AR |
| PIK3 | AR |
| BLNK | AR |
| TCF3 | AR and AD |
| LRRC8 | AD |
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