AML	acute myeloid leukemia
BMM	bone marrow microenvironment
LSCs	leukemic stem cells
HIF	hypoxia inducible factor
BM	bone marrow
HSCs	hematopoietic stem cells
PHD	prolyl hydroxylases
VHL	von Hippel-Lindau
CBP	CREB-binding protein
HRE	hypoxia responsive elements
Treg	regulatory T cells
STAT5	signal transducer and activator of transcription 5
VEGF	vascular endothelial growth factor
SDF1	stromal cell-derived factor 1
SCF	stem cell factor
Ang2	angiopoietin 2
Angptl	angiopoietin-likes
IGF-2	insulin-like growth factor 2
IGFBP	insulin-like growth factor-binding protein
FOXO	forkhead box O
CDKN	cyclin-dependent kinase inhibitor
ROS	reactive oxygen species
OXPHOS	oxidative phosphorylation
CML	chronic myeloid leukemia
TCA	tricarboxylic acid
UDP-GlcNAc	uridine diphosphate N-acetylglucosamine
UDP-GalNAc	uridine diphosphate N-acetylgalactosamine
2-HG	2-hydroxyglutarate
PDK1	pyruvate dehydrogenase 1
GSH	reduced glutathione
GSSG	oxidized glutathione
COX 4-1	cytochrome C oxidase subunit 4 isoform 1
COX 4-2	cytochrome C oxidase subunit 4 isoform 2
WHO	world health organization
OS	overall survival
EFS	event free survival
IDH	isocitrate dehydrogenase
α-KG	α-ketoglutarate
TET	ten-eleven translocation
SDH	succinate dehydrogenase
UQ	ubiquinone
UQH2	ubiquinol
NDRG3	N-Myc downstream-regulated 3
ERK1/2	extracellular-signal-regulated kinase 1/2
GPR91	G-protein-coupled receptor
mTOR	mammalian target of rapamycin
CXCL12	C-X-C motif chemokine ligand 12
CXCR4	C-X-C motif chemokine receptor 4
FLT3	FMS-like tyrosine kinase 3
MIF	macrophage migration factor
IL-8	interleukin-8
MSC	mesenchymal stromal cells
PI3K	phosphoinositide 3-kinase
PKB or AKT	protein kinase B
AXL	receptor tyrosine kinase
ITD	internal tandem duplication
NPM1	nucleophosmin
LDH	lactate dehydrogenase
Ara-C	cytarabine arabinoside
XIAP	X-linked inhibitor of apoptosis
PML	promyelocytic leukemia
RAR- α	retinoic acid receptor-α
APL	acute promyelocytic leukemia
ATRA	trans retinoic acid
HAP	hypoxia-activated prodrugs
BCL-2	B-cell lymphoma 2
MCL-1	myeloid cell lymphoma 1
PD-L1	programmed death ligand 1
mAb	monoclonal antibody
MCT	monocarboxylate transporter
AKR1C3	aldo-keto reductase 1C3
Br-iPM	bromo-isophosphoramide mustard