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Schematic drawing representing the potential influence of CerK in the context of skeletal muscle atrophy associated with cancer or corticosteroids. Abbreviations: C1P, ceramide 1-phosphate; Dexa, dexamethasone; C8-cer, C8-ceramide; CerK-shRNA, short hairpin RNAs targeting CerK mRNA; C26-CM, conditioned media from C26 carcinoma cells; LLC-CM, conditioned media from Lewis lung carcinoma cells.
