Table 4.
Rabbit PLF model.
| Rabbit PLF Model | ||||
|---|---|---|---|---|
| Author (Year) | Carrier | BMP Dose (µg) | Time (Weeks) | Sample Size (n) |
| Boden et al. (1995) | DBM, Biocoral/ Collagen | 100 and 300 | 5 | 14–16 |
| Itoh et al. (1999) | Collagen | 10, 50, and 200 | 24 | 6 |
| Louis-Ugbo et al. (2001) | BCP, Collagen/BCP |
3000/mL | 5 | 18 |
| Jenis et al. (2002) | Collagen | - | 3 and 12 | 8 |
| Konishi et al. (2002) | Autograft/HA | 200 | 2, 4, and 6 | 2–7 |
| Suh et al. (2002) | Collagen/BCP, BCP |
860 | 5 | 14 |
| Minamide et al. (2003) | TCP cement, True bone ceramics, Collagen |
100 | 3 and 6 | 5–10 |
| Namikawa et al. (2005) | TCP/PLA-DX-PEG | 7.5, 15, and 30 | 6 | 5 |
| Valdes et al. (2007) | - | 6 | 18 | |
| Dohzono et al. (2009) | TCP | 5, 15, 50, and 150 | 4 and 8 | 5–8 |
| Lee JW et al. (2011) | Heparin—conjugated PLGA nanospheres, PLGA nanospheres |
20 | 12 | 12 |
| Lee JH et al. (2012) | HA | 10, 50, 200, and 500 | 3 and 6 | 14 |
| Vukicevic et al. (2019) | Autologous blood coagulum, Autologous blood coagulum/Allograft |
125, 250, 500, and 1000 | 14 | 4 |