Table 6.
Sheep and non-humane primate PLF models.
| Sheep PLF Model | ||||
|---|---|---|---|---|
| Author (Year) | Carrier | BMP Dose (µg) | Time (Weeks) | Sample Size (n) |
| Pelletier et al. (2014) | TCP | 1050, 3500, and 10,500 | 12 | 12 |
| Toth et al. (2016) | Collagen/BCP, Collagen-ceramic sponge |
750 and 1500/cm3 | 24 | 12–24 |
| Grgurevic et al. (2020) | Autologous blood coagulum, Autologous blood coagulum/Allograft |
500 and 1500 | 27 | 6–10 |
| NHP PLF Model | ||||
| Author (Year) | Carrier | BMP Dose ( µ g) | Time (Weeks) | Sample Size (n) |
| Boden et al. (1999) | BCP | 6000, 9000, and 12,000 | 24 | 4–12 |
| Suh et al. (2002) | Ceramic/Collagen | 9000 | 24 | 4 |
| Akamaru et al. (2003) | Collagen/BCP Collagen/Allograft |
3000 | 24 | 6 |