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. 2021 Jul 6;9:e11735. doi: 10.7717/peerj.11735

Table 2. Biochemical variables of the individuals.

Non-Progression (n = 214) Progression
(n = 40)
Total
(n = 254)
p-value
Hb (g/L) 134.98 ± 16.67 127.95 ± 13.99 133.87 ± 16.46 0.01
TSH (mIU/L) 2.11 ± 1.88 1.88 ± 2.13 2.08 ± 1.92 0.48
FT3 (pmol/L) 4.37 ± 1.14 4.11 ± 0.49 4.33 ± 1.07 0.15
FT4 (pmol/L) 15.95 ± 5.84 15.56 ± 1.95 15.89 ± 5.42 0.68
Total protein (g/L) 68.83 ± 6.56 66.39 ± 4.73 68.44 ± 6.36 0.03
Albumin (g/L) 41.13 ± 3.61 38.92 ± 2.88 40.77 ± 3.59 <0.01
Direct bilirubin (μmol/L) 4.05 ± 2.11 3.96 ± 1.99 4.03 ± 2.09 0.80
Indirect bilirubin (μmol/L) 8.67 ± 4.60 7.26 ± 3.85 8.45 ± 4.51 0.07
Creatine (mol/L) 82.66 ± 29.78 80.75 ± 38.38 82.20 ± 31.26 0.72
Uric acid (μmol/L) 340.83 ± 108.58 343.98 ± 102.87 342.16 ± 107.51 0.90
FBG (mmol/L) 11.58 ± 7.53 13.93 ± 7.67 11.94 ± 7.60 0.07
HbA1c (%) 8.74 ± 2.12 9.77 ± 2.21 8.90 ± 2.16 <0.01
Total cholesterol (mmol/L) 4.84 ± 1.03 5.06 ± 1.28 4.88 ± 1.07 0.23
Triglyceride (mmol/L) 2.19 ± 2.18 3.13 ± 4.12 2.34 ± 2.59 0.03
HDL (mmol/L) 1.31 ± 0.35 1.33 ± 0.31 1.31 ± 0.34 0.66
LDL (mmol/L) 2.65 ± 0.63 2.91 ± 1.02 2.69 ± 0.71 0.03
Albuminuria (mg/h) 56.73 ± 141.89 282.10 ± 394.84 92.22 ± 218.52 <0.01

Note:

Hb, haemoglobin; TSH, thyroid stimulating hormone; FT3, free triiodothyronine; FT4, free thyroxine; FBG, fasting blood glucose; HDL, high-density lipoprotein; LDL, low-density lipoprotein; HbA1c, glycosylated haemoglobin A1c.