Table 1.
Group | PCa | Non-PCa | P |
---|---|---|---|
Cases, n (%) | 236 (44.6) | 293 (55.4) | |
Age (year) | |||
Median (IQR) | 70 (66–77) | 66 (62–70) | |
Mean±s.d. | 71.26±7.46 | 66.71±6.72 | <0.001a |
PSA value (ng ml−1) | |||
Median (IQR) | 15.68 (8.49–36.79) | 8.32 (5.82–12.41) | |
Mean±s.d. | 56.51±158.17 | 10.79±9.75 | <0.001a |
Prostate volume (ml) | |||
Median (IQR) | 40.13 (30.99–61.77) | 45.79 (61.78–82.00) | |
Mean±s.d. | 49.64±28.56 | 67.09±32.96 | <0.001a |
PSAD (ng ml−2) | |||
Median (IQR) | 0.389 (0.198–0.987) | 0.141 (0.098–0.198) | |
Mean±s.d. | 1.209±3.243 | 0.194±0.233 | <0.001a |
TZ-PSAD (ng ml−2) | |||
Median (IQR) | 0.716 (0.394–1.659) | 0.255 (0.149–0.385) | |
Mean±s.d. | 1.853±4.258 | 0.383±0.523 | <0.001a |
PZ-PSAD (ng ml−2) | |||
Median (IQR) | 0.659 (0.235–2.274) | 0.093 (-0.044–0.228) | |
Mean±s.d. | 6.053±31.264 | 0.208±0.984 | <0.001a |
DRE (n) | |||
Normal | 112 | 265 | |
Positive | 124 | 28 | <0.001b |
TRUS findings (n) | |||
Normal | 87 | 252 | |
Positive | 149 | 41 | <0.001b |
mpMRI findings (n) | |||
Normal | 57 | 215 | |
Positive | 179 | 78 | <0.001b |
aMann-Whitney U test; bχ2 analysis. PCa: prostate cancer; IQR: interquartile range; s.d.: standard deviation; PSA: prostate-specific antigen; PSAD: prostate-specific antigen density; TZ-PSAD: transition zone prostate-specific antigen density; PZ-PSAD: peripheral zone prostate-specific antigen density; DRE: digital rectal examination; TRUS: transrectal ultrasound; mpMRI: multiparameter magnetic resonance imaging