Supplementary Table 3.
Sensitivity, specificity, and area under the receiver operating characteristic curve of peripheral zone prostate-specific antigen density, prostate-specific antigen, prostate-specific antigen density, and transition zone prostate-specific antigen density for predicting prostate cancer
| PSA (ng ml−1) | Variable | Best cutoff | Sensitivity (%) | Specificity (%) | AUC-ROC |
|---|---|---|---|---|---|
| 4.0–10.0 | PZ-PSAD | 0.105 | 70.7 | 72.1 | 0.770 |
| PSA | 6.455 | 68.0 | 53.1 | 0.592 | |
| PSAD | 0.142 | 69.3 | 69.3 | 0.730 | |
| TZ-PSAD | 0.289 | 74.7 | 73.2 | 0.766 | |
| 10.1–20.0 | PZ-PSAD | 0.436 | 68.8 | 86.5 | 0.823 |
| PSA | 14.05 | 58.5 | 67.7 | 0.621 | |
| PSAD | 0.298 | 67.5 | 84.4 | 0.799 | |
| TZ-PSAD | 0.844 | 84.4 | 63.5 | 0.769 | |
| 4.0–20.0 | PZ-PSAD | 0.258 | 59.2 | 83.3 | 0.785 |
| PSA | 7.895 | 67.1 | 52.0 | 0.630 | |
| PSAD | 0.208 | 61.8 | 82.2 | 0.762 | |
| TZ-PSAD | 0.302 | 81.6 | 66.2 | 0.775 | |
| >20.0 | PZ-PSAD | 1.803 | 84.5 | 77.8 | 0.870 |
| PSA | 39.21 | 67.9 | 77.8 | 0.750 | |
| PSAD | 0.801 | 76.2 | 77.8 | 0.797 | |
| TZ-PSAD | 0.685 | 90.5 | 61.1 | 0.728 |
PSA: prostate-specific antigen; PSAD: prostate-specific antigen density; TZ-PSAD: transition zone prostate-specific antigen density; PZ-PSAD: peripheral zone prostate-specific antigen density; ROC: receiver operating characteristic; AUC-ROC: area under the ROC curve-ROC