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. 2021 Jul 2;14(13):3722. doi: 10.3390/ma14133722

Table 1.

Characteristics of TCE metals with the influence of these metals on living organisms.

Metal General Description Impact Ref
Germanium
  • widely distributed in the body and its accumulation and retention in the organs depending on the chemical form of germanium.

  • no definite evidence for the mutagenicity of germanium but under certain conditions it inhibits the mutagenic activity of other substances.

  • causes toxic effects in humans.

  • organic compounds destroy cancer cells and reveal antineoplastic properties in human.

  • inorganic forms (especially when inhaled) may be toxic in high doses.

[6,13,14]
Thallium
  • very toxic.

  • its salts are considered to be the most toxic compounds known.

  • toxicity of Tl has not been greatly studied, but its harmful impact has been observed on both humans and animals.

  • contents of Tl in most mammalian tissues <200 µg kg−1.

  • increased level, at 500 µg kg–1 (in the skin)

  • is easily absorbed through the skin.

  • ingested and inhaled Tl is also harmful to organisms.

  • general exposure has been observed in the population living in the vicinity of a cement plant (discharges high-Tl containing dust).

  • other Tl sources: coal combustion, roasting of sulfide concentrates, and manufacturing of Tl-containing products.

[6,14]
Tellurium
  • has no biological role.

  • all its compounds are highly toxic.

  • considered to be a teratogenic agent, however, acute poisoning is rare.

  • workers exposed to 0.5 to <10 µg Te m–3 have a garlic-like odor (a symptom of the Te intoxication).

  • permissible exposure limits for Te in inhaled air vary for different compounds, from 0.1 mg m–3 for elemental and dioxide Te, to 10 mg m–3 for telluride compounds.

[14]