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. Author manuscript; available in PMC: 2021 Sep 24.
Published in final edited form as: Nature. 2021 Mar 24;592(7855):623–628. doi: 10.1038/s41586-021-03365-x

Figure 2 |. Vaccine-elicited antibody responses against vaccine-matched viruses in mice, ferrets, and NHPs.

Figure 2 |

a, Hemagglutination inhibition (HAI) and b, microneutralization (MN) titers in immune sera. Groups of BALB/cJ mice (N = 10), ferrets (N = 9), and rhesus macaques (N = 4) were used in each experiment. Each symbol represents an individual animal and the horizontal bar indicates the geometric mean of the group. Individual NHPs are identified by unique symbols. Statistical analysis was performed using one-sided nonparametric Kruskal–Wallis test with Dunn’s multiple comparisons. All animal experiments except for NHPs were performed at least twice and representative data are shown.