Table 4.

Results of receiver operating characteristic analysis showing the predictive value of c-reactive protein, procalcitonin, fibrinogen, white blood cell and neutrophil-to-lymphocyte ratio for absence/presence of gastric leak after laparoscopic sleeve gastrectomy

	AUC	95% CI	SE	Cutoff value	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)
CRP
Preoperative	0.631	0.468-0.795	0.083	0.7	100	41.44	8.45	100
1 day after	0.550	0.285-0.815	0.135	7.24	33.33	98.20	50.03	96.46
3 days after	0.984	0.951-1	0.016	7.33	100	90.09	35.30	100
5 days after	0.966	0.901-1	0.033	5.59	83.33	100	100	99.11
PCT
Preoperative	0.615	0.453-0.777	0.083	0.04	100	34.23	7.60	100
1 day after	1	1-1	0	0.55	100	100	100	100
3 days after	0.996	0.985-1	0.005	0.14	83.33	99.10	83.35	99.10
5 days after	0.967	0.905-1	0.031	1.64	83.33	100	100	99.11
Fibrinogen
Preoperative	0.664	0.503-0.824	0.082	328	100	38.74	8.11	100
1 day after	0.553	0.291-0.814	0.133	402	33.33	99.10	66.69	96.49
3 days after	0.985	0.956-1	0.015	388	100	90.99	37.51	100
5 days after	0.957	0.876-1	0.041	529	83.33	100	100	99.11
WBC
Preoperative	0.665	0.486-0.844	0.091	6.5	100	34.23	7.60	100
1 day after	0.652	0.325-0.978	0.166	11.84	66.67	81.98	16.67	97.85
3 days after	0.984	0.951-1	0.016	10.18	100	89.19	33.34	100
5 days after	0.949	0.856-1	0.048	6.57	83.33	100	100	99.11
NLR
Preoperative	0.724	0.567-0.881	0.080	1.74	83.33	73.87	14.71	98.79
1 day after	1	1-1	0	2.74	100	100	100	100
3 days after	1	1-1	0	3.22	100	100	100	100
5 days after	1	1-1	0	3.64	100	100	100	100

AUC: Area under the curve, CI: Confidence interval, SE: Standard error. PPV: Positive predictive value. NPV: Negative predictive value, WBC: White blood cells; NLR: Neutrophil-to-lymphocyte ratio, PCT: Procalcitonin, CRP: C-reactive protein