Table 1. Summary of diagnostic testing.
CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; HIV, human immunodeficiency virus; LAD, left anterior descending artery; LGE, late gadolinium enhancement; LVEDVi, left ventricular end-diastolic volume index; LVEF: left ventricular ejection fraction; LVIDd: left ventricular end-diastolic internal dimension; MRI, magnetic resonance imaging; RSV, respiratory syncytial virus; RVEDVi, right ventricular end-diastolic volume index; RVEF: right ventricular ejection fraction
| Cardiovascular Adverse Event | Age (years) | Gender | Viral serologies | Cardiac Biomarkers | Inflammatory Markers | Transthoracic Echocardiogram | Cardiac MRI | Coronary Evaluation |
| Myocarditis | ||||||||
| Patient 1 | 19 | Male | HIV, influenza, RSV, and SARS-CoV-2 negative | Troponin T: 1.37 ng/mL (reference range: <0.03 ng/mL) | CRP: 1.8 mg/dL (reference range: <0.80 mg/dL); ESR: 26 mm/hour (reference range: < 20 mm/hour) | LVEF: 47%; LVIDd: 4.7 cm; Normal RV size and function; No valvular disease | LVEF: 56%; LVEDVi: 84 mL/m2; RVEF: 54%; RVEDVi: 86 mL/m2; Subepicardial LGE involving the basal to mid lateral wall, with corresponding elevated native T1 and T2 values | Coronary angiography: No coronary artery disease or anomalies |
| Patient 2 | 18 | Male | HIV, influenza, RSV, and SARS-CoV-2 negative | High-sensitivity troponin: 7,206 ng/L  32,140 ng/L (reference range: <15 ng/L) |
CRP: 74.2 mg/L (reference range: <10 mg/L); ESR: 29 mm/hour (reference range: <15 mm/hour) | LVEF: 59%  50%, LVIDd: 4.8 cm; Normal RV size and function; No valvular disease |
LVEF: 53%; LVEDVi: 101 mL/m2; RVEF: 49%; RVEDVi: 118 mL/m2; Subepicardial LGE involving the mid lateral wall, with corresponding elevated native T1 and T2 values | Coronary computed tomography angiography: No coronary artery disease or anomalies |
| Stress Cardiomyopathy | ||||||||
| Patient 1 | 60 | Female | SARS-CoV-2, influenza, and RSV negative | Troponin T: 0.129 ng/mL (reference range: <0.03 ng/mL) | Not checked | LVEF: 44%; LVIDd: 3.5 cm; Normal RV size and function; Apical akinesis | Not performed | Coronary angiography: Patent LAD stent |
| Pericarditis | ||||||||
| Patient 1 | 21 | Female | SARS-CoV-2, HIV negative | Troponin T: undetectable | CRP: 72.6 mg/L (reference range: <3 mg/L); ESR: 9 mm/hour (reference range: <19 mm/hour) | LVEF: 60%; LVIDd: 4.5 cm; Normal RV size and function; Small pericardial effusion | Not performed | Not performed |
| Patient 2 | 61 | Female | SARS-CoV-2 negative | Troponin T: undetectable | CRP: 23.1 mg/dL (reference range: <0.80 mg/dL); ESR: 81 mm/hour (reference range: <15 mm/hour) | LVEF: 65%; LVIDd: 3.6 cm; Normal RV size and function; Small to moderate circumferential pericardial effusion | Not performed | Not performed |