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. 2021 Apr 28;144(2):144–158. doi: 10.1161/CIRCULATIONAHA.120.052788

Figure 6.

Figure 6.

Single meal inhibits monocytic mitochondrial function. A, Scheme of the study protocol with a picture of a representative pizza containing 9.8±0.3 g NaCl. Before, 3 hours and 8 hours after the meal challenge, monocytes were isolated from 10 male and 10 female volunteers (n=20 per time point). B, Plasma Na+, (C) monocytic basal oxygen consuption rate (OCR) in relation to baseline, and (E) TMREhigh monocytes in relation to baseline at baseline, 3 hours, and 8 hours after pizza. D, Relation between fold-change in monocytic basal OCR and difference in plasma Na+ as single time point comparison between 3 hours after pizza and baseline. B, C, and E, Data were analyzed by Friedman test with Benjamini-Hochberg false discovery rate (FDR) correction. D, Relationship between the change in plasma Na+ and the change in basal OCR (of 3 hours compared with baseline) was determined by Pearson correlation and linear regression analysis. TMRE indicates tetramethylrhodamine ethyl ester.