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. 2021 Jun 24;26(13):3874. doi: 10.3390/molecules26133874

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Metaspread with use of whole chromosome painting-WCP and M-band and karyotypes: (A) metaspread with WCP10 with orange dye shows gain of genetic information from chromosome 10; (B) karyotype on patients with duplication of long arm of chromosome 10: 46, XX, dup (10) (q11q26); (C) multicolor chromosome banding probe on chromosome 18; (D) zoomed picture of 3 chromosomes 18 with M-band probes; and (E) karyotype of newborn with trisomy of 18 presented in rare form: 46, XX, der (13;18) (q10; p10) +18 (source: Author with permission of Medirex laboratory).