Table 3.
Summary of the cytotoxicity and anti-diabetic activity of GT fractions.
| Fraction Number | Cytotoxicity (µg/mL), Safe Up to: |
GLUT4 Translocation (% Relative to Controls) at 125 µg/mL | |
|---|---|---|---|
| − Insulin Relative to Control without Insulin | + Insulin Relative to Control with Insulin | ||
| 1 | 500 | 1.14 | 0.94 |
| 2 | 500 | 1.18 | 1.40 |
| 3 | 500 | 1.10 | 1.00 |
| 4 | 250 | 1.59 | 1.08 |
| 5 | 125 | 1.30 | 1.40 |
| 6 | 250 | 1.65 | 1.95 |
| 7 | 250 | 1.38 | 0.96 |
| 8 | 500 | 1.36 | 1.19 |
| 9 | 500 | 1.46 | 1.24 |
| 10 | 500 | 1.42 | 1.48 |
GT, Gundelia tournefortii; GLUT4, glucose transporter type 4.