Lack of significant effects of 2-(nicotinamide)-1,3,4-thiadiazole (TGN-020) on the electrical activity of VP neurons. A, Representative episodes of the firing activity of VP neurons in the presence of TGN-020 (10 μmol/L, 10 min) in patch-clamp recording, taken at 1 min before and 10 min after TGN-020 respectively. B, Bar graphs illustrating the lack of significant effect of TGN-020 on the firing rate (a), AP amplitude (b) and duration (c), and AHP amplitude (d), duration (e) and decay slope (f) in comparison to the control (CTL)