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. 2021 Jul 9;16(7):e0254367. doi: 10.1371/journal.pone.0254367

Fig 1. Detection of specific antibody responses (IgG) against SARS-CoV-2 S Protein RBD domain (S-RBD) in rhesus macaques and rabbits as detected by the multiplex assay.

Fig 1

Multiplex assay was performed to detect IgG antibodies against SARS-CoV-2 S-RBD, SARS-CoV S & N, MERS-CoV S-RBD and S proteins of 4 common coronaviruses. IgG antibodies only to SARS-CoV-2 (S-RBD) antigen as determined in a multiplex microbead assay format are shown as MFI here. MFI values in log10 scale with Interquartile Range (IQR) are shown. Healthy monkeys from UCD (UC Davis) and CR (Charles River), and rabbits were included as negative control animals. Statistical significance was tested by one-way ANOVA and Tukey’s multiple comparison test (P value <0·0001 is denoted by ****).