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. 2021 Jul 9;7(28):eabh3457. doi: 10.1126/sciadv.abh3457

Fig. 7. TRPM7 overexpression in HT-1080 fibrosarcoma cells inhibits invasive metastatic lesion formation.

Fig. 7

(A) Representative images showing metastatic lesions formed by control (YFP-C1) or TRPM7-overexpressing (TRPM7-YFP) HT-1080 cells. Images are maximum intensity projections of 3D reconstructions. Insets show YFP signal alone. Quantification of average (B) cancer cell length, (C) cancer cell number, and (D) cancer cell track velocity within the metastatic lesions formed by control or TRPM7-overexpressing HT-1080 cells. Data are means + SD with statistical comparison made using unpaired t test. Scale bar, 50 μm.