Table 2.
HDACs | Lymph node status | Cases | HR (95%CI) | P value |
HDAC1 | Negative | 76 | 0.4 (0.17–0.92) | .025∗ |
Positive | 437 | 0.54 (0.41–0.7) | .0000028∗ | |
HDAC2 | Negative | 76 | 2.44 (0.72–8.28) | .14 |
Positive | 437 | 0.84 (0.64–1.1) | .12 | |
HDAC3 | Negative | 76 | 1.49 (0.66–3.4) | .34 |
Positive | 437 | 1.2 (0.92–1.56) | .18 | |
HDAC4 | Negative | 76 | 1.9 (0.82–4.38) | .13 |
Positive | 437 | 1.79 (1.36–2.36) | .000026∗ | |
HDAC5 | Negative | 76 | 0.54 (0.22–1.32) | .17 |
Positive | 437 | 1.74 (1.34–2.27) | .000026∗ | |
HDAC6 | Negative | 76 | 2.93 (1.26–6.85) | .0094∗ |
Positive | 437 | 1.83 (1.41–2.38) | .0000051∗ | |
HDAC7 | Negative | 76 | 1.77 (0.69–4.49) | .23 |
Positive | 437 | 1.55 (1.18–2.04) | .0014∗ | |
HDAC8 | Negative | 76 | 1.84 (0.8–4.21) | .14 |
Positive | 437 | 1.58 (1.2–2.06) | .00084∗ | |
HDAC9 | Negative | 76 | 3.56 (1.39–9.12) | .0049∗ |
Positive | 437 | 1.28 (0.95–1.71) | .1 | |
HDAC10 | Negative | 76 | 1.85 (0.62–5.54) | .26 |
Positive | 437 | 1.91 (1.45–2.52) | .0000028∗ | |
HDAC11 | Negative | 76 | 2.08 (0.91–4.73) | .075 |
Positive | 437 | 1.4 (1.05–1.86) | .02∗ |
GC = gastric cancer; HDACs = histone deacetylases; HR = hazard ratio.
P value < .05.