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. 2021 Jul 9;100(27):e26535. doi: 10.1097/MD.0000000000026535

Table 3.

The subgroups analysis for lincRNA-ROR and OS in cancer patients.

Pooled Data Test for heterogeneity
Subgroups Number of Studies Case (n) High expression (n) High expression (%) HR 95% CI P-value P-value I2 (%)
Univariate analysis
Histological type
 Digestive cancer 8 671 294 43.8 2.70 1.85–3.94 <.001 <.001 75.6
 Other cancer 5 447 192 43.0 2.12 1.56–2.88 <.001 .996 0.0
Case (n)
 < 80 6 275 121 44.0 3.20 2.07–4.95 <.001 .158 37.3
 ≥ 80 7 843 365 43.3 2.10 1.60–2.74 <.001 .038 54.9
Follow-up (mo)
 < 60 4 223 63 28.3 3.35 2.35–4.77 <.001 .555 0.0
 ≥ 60 9 895 423 47.3 2.21 1.65–2.95 <.001 .010 60.3
Quality
 High 11 982 486 49.5 2.33 1.79–3.05 <.001 .006 59.4
 Low 2 136 63 46.3 3.64 1.92–6.88 <.001 .289 10.9
Multivariate analysis
Histological type
 Digestive cancer 4 394 207 52.5 3.73 1.51–9.22 .004 <.001 87.6
 Other cancer 1 229 113 49.3 2.98 1.21–7.37 .018 - -
Case (n)
 < 80 2 139 75 54.0 7.17 4.07–12.65 <.001 .987 0.0
 ≥ 80 3 484 245 50.6 2.18 1.20–3.98 .011 .067 63.0

CI = confidence interval, HR = hazard ratio, OS = overall survival.